I am probably not quite smart enough to review this book, but I'll give it my best shot.
Clearly, it is a book about perceiving and perceptions of beauty, whether that's body shape, rendered in art, elderly vs. youth, or the natural world (not much of that). But there's so much else in here that I can't fit into that theme. Sure, a book doesn't (and probably shouldn't) have only one theme, but there's a whole separate set of treatises on the role of academia, all kinds of politics, and, of course, race and ethnicity. It's a long book, and it can basically hold all of this, but it means I got lost in the comings and goings of the characters.
So, I read the book and was intrigued by the multiple lives and their method of conversing and communicating with others, but in essence it felt like a set of short stories strung together with a common thread among them. I kept being thrown off the scent into the next story, trying to figure out how it hung with the rest.
Also, most of this felt like an apology. Oh, Levi is acting this way for this reason. And Carl has a different reason for acting as he does. And Kiki. And ridiculous, dumb-ass Howard. Why apologize for how different people think and react? You're telling, not showing, then. Isn't that a cardinal sin of writing?